Post by Garrett WollmanPost by Aidan KehoeMany of my patients are happy to pay for GLP-1 agonists out of pocket; the
cash price here is reasonable enough that the substantial reduced outgoings
on food balance it out. The patients are in general not wealthy.
I understand US out of pocket prices are of the order of 1000 USD, so
it’s a different decision over there.
Many of the older drugs in this family are either off-patent or about
to be. (Tirzepatide, which is slightly newer, still has a few more
years to run.)
I hope another manufacturer starts marketing exenatide in this market,
AstraZeneca seem to have pulled back. There’s plenty of sales volume to go
around, and there is evidence that the GLP-1 agonists slow progression of
Parkinson’s, and the studies used exenatide in particular. And we’ve very
little that slows progression of Parkinson’s.
Post by Garrett WollmanIt is very common for pharmacy benefit managers to use
a three-tier system: the lowest patient cost for generic medications,
a middle price for "formulary" brand-name medications, and the highest
price for all other brand-name medications. A common tiering might be
$10 for the lowest tier, $25 for the middle, and $50 for the highest
-- typically for a month's supply, but depending on the plan and the
indication, that might be for three months' supply instead.[1]
-GAWollman
[1] On my plan, for reasons I am entirely unable to fathom, a
three-month supply of atorvastatin is free, but a three-month supply
of metformin costs four dollars and change.
Is it extended-release metformin? In the grand scheme of things that’s
relatively new and so it costing a bit more than a non-extended-release
atorvastatin is understandable. If it’s the normal metformin that has been
kicking around for half a century or longer that would be a surprise.
“NHS indicative prices” from the British National Formulary, giving a rough
guide as to what medications cost the taxpayer in Britain currently:
Metformin 500 mg tablets, Almus Pharmaceuticals Ltd, 84 tablet: £ 1.92
Sukkarto SR 750 mg tablets, Morningside Healthcare Ltd (extended-release
metformin), 56 tablets, £ 2.87
Atorvastatin 20 mg tablets, Milpharm Ltd, 28 tablet, £ 0.80
Wegovy FlexTouch 0.25 mg / 0.37 mL (semaglutide weight loss injection), 1
pre-filled disposable injection: £ 73.25
Bydureon 2 mg/0.85 mL, 4 pre-filled disposable injections (exenatide):
£ 73.36.
--
‘As I sat looking up at the Guinness ad, I could never figure out /
How your man stayed up on the surfboard after fourteen pints of stout’
(C. Moore)